The Aulin and 'a drug used and abused by many people, the more' use it even for a simple headache, often without consulting the doctor and without knowing the real effects, and many do not know that you and 'remove from the discussion of trade because it was considered dangerous ...
But first things first: the Aulin and' an anti-inflammatory drug / anti-rheumatic drugs (ie 'an NSAID, the same category they belong to Aspirin or Tachipirina). The active and 'nimesulide, a molecule anti-inflammatory, analgesic and antipyretic (ie' lower fever). Since the drug on the market since 1985, patent protection has expired for some time and is therefore available both as a brand name drug (Aulin) and as a generic drug or equivalent. Italy alone accounts for 60% of the consumption of the drug. In 2002, Spain and Finland have withdrawn from the market in medicines containing nimesulide for suspected liver toxicity. In countries like U.S. and Japan nimesulide was never submitted to obtain registration. Studies of the EMEA in 2003, however, considered acceptable benefit / risk ratio of the active ingredient, especially in light of its particularly favorable gastric tolerability profile. From May 15, 2007 the Agency also of Irish drug has suspended the sale, following a report of 6 cases of liver failure in people who had made long-term use. In these subjects were required a liver transplant. On December 3, 2007 RTÉ Irish public television aired a program 's investigation to discuss the link between the intake of Nimesulide and more than 300 cases of liver injury and death cases registered by the European pharmacovigilance systems. Despite several attempts to withdraw from the market is still on the market prinipalmente for economic and political reasons. In May 2008, the SIF (Italian Society of Pharmacology) contains a note quoting verbatim, "If it (nimesulide) remains on the market as well as in Italy in well 16 other European countries, including France, Portugal, Switzerland, Hungary, is why the European regulatory agency found that, despite the independently determined by some countries, their profile of risk / benefit still remains favorable. "The IMS Also, remember that the decision taken by the EMEA "The decision was passed by a majority of countries that are part of the European Community and that they all share participation in decisions of EMEA." The Nimesulide is an active ingredient present in the following medicines: present in drugs: Aulin, Algimesil, analgesic, Areuma, Dimesul, Domes, EFRIDOL, Eudolene, Fansulide, Flolid, Isodol, Ledolid, Ledoren, Nerelid, nide, Nimenol, Nims, Noxalide, Resulin, Solving, Sulidamor, Fansidol, Sulide, Idealid, Delfos, Domes, Noalgos, Algolider, Aulin, Fansidol, Mesulid, Nimesil, Remove, Migraless, Edemax, Mesulid Fast, Nimedex and many generics. And in my humble opinion 'that it is right, lest too alarmist, also because' the leaflet enclosed in the package are all carefully gia'citati gi side effects, and e 'is already proved that any drug can cause dangerous side effects: each time accept a compromise between benefits and possible risks. There is no medicine to one hundred percent sure, but there is no doubt that drugs are produced very controlled. If we take drugs without Read the package leaflet or, as in the case dell'Aulin, the onset of every little pain that does not justify the administration can not claim some beneficial effects on health. The mentality to fight is to take a pill / bag to a minimum symptom.
But first things first: the Aulin and' an anti-inflammatory drug / anti-rheumatic drugs (ie 'an NSAID, the same category they belong to Aspirin or Tachipirina). The active and 'nimesulide, a molecule anti-inflammatory, analgesic and antipyretic (ie' lower fever). Since the drug on the market since 1985, patent protection has expired for some time and is therefore available both as a brand name drug (Aulin) and as a generic drug or equivalent. Italy alone accounts for 60% of the consumption of the drug. In 2002, Spain and Finland have withdrawn from the market in medicines containing nimesulide for suspected liver toxicity. In countries like U.S. and Japan nimesulide was never submitted to obtain registration. Studies of the EMEA in 2003, however, considered acceptable benefit / risk ratio of the active ingredient, especially in light of its particularly favorable gastric tolerability profile. From May 15, 2007 the Agency also of Irish drug has suspended the sale, following a report of 6 cases of liver failure in people who had made long-term use. In these subjects were required a liver transplant. On December 3, 2007 RTÉ Irish public television aired a program 's investigation to discuss the link between the intake of Nimesulide and more than 300 cases of liver injury and death cases registered by the European pharmacovigilance systems. Despite several attempts to withdraw from the market is still on the market prinipalmente for economic and political reasons. In May 2008, the SIF (Italian Society of Pharmacology) contains a note quoting verbatim, "If it (nimesulide) remains on the market as well as in Italy in well 16 other European countries, including France, Portugal, Switzerland, Hungary, is why the European regulatory agency found that, despite the independently determined by some countries, their profile of risk / benefit still remains favorable. "The IMS Also, remember that the decision taken by the EMEA "The decision was passed by a majority of countries that are part of the European Community and that they all share participation in decisions of EMEA." The Nimesulide is an active ingredient present in the following medicines: present in drugs: Aulin, Algimesil, analgesic, Areuma, Dimesul, Domes, EFRIDOL, Eudolene, Fansulide, Flolid, Isodol, Ledolid, Ledoren, Nerelid, nide, Nimenol, Nims, Noxalide, Resulin, Solving, Sulidamor, Fansidol, Sulide, Idealid, Delfos, Domes, Noalgos, Algolider, Aulin, Fansidol, Mesulid, Nimesil, Remove, Migraless, Edemax, Mesulid Fast, Nimedex and many generics. And in my humble opinion 'that it is right, lest too alarmist, also because' the leaflet enclosed in the package are all carefully gia'citati gi side effects, and e 'is already proved that any drug can cause dangerous side effects: each time accept a compromise between benefits and possible risks. There is no medicine to one hundred percent sure, but there is no doubt that drugs are produced very controlled. If we take drugs without Read the package leaflet or, as in the case dell'Aulin, the onset of every little pain that does not justify the administration can not claim some beneficial effects on health. The mentality to fight is to take a pill / bag to a minimum symptom.
News taken from various sources.
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